Ditapis dengan
Preparation and Characterization of Gliclazide Solid Dispersion in Binary and…
ABSTRACT Objective: The objective of this research was to improve the dissolution rate of gliclazide by solid dispersion technique with poloxamer 188, HPMC, and Eudragit® Methods: Solid dispersions were prepared by solvent evaporation methods in the binary and ternary system. In binary system gliclazide was mixed with poloxamer188 in the ratio of 1:0.5, 1:0.75, 1:1, 1:1.5 and 1:2, with HPMC …
- Edisi
- 2016
- ISBN/ISSN
- -
- Deskripsi Fisik
- -
- Judul Seri
- -
- No. Panggil
- 001 War p
Enhancing Dissolution Rates of Gliclazide via Co-crystallization with Nicotin…
Abstract Gliclazide is a drug with poor water solubility and high permeability (BCS II), The absorption rate of this drug, when taken orally is controlled by dissolution rate in the gastrointestinal tracts. Co-crystallization method is widely used to improve the dissolution rate of this type of drug. This study aims to improve the dissolution rate of gliclazide by Co-crystallization method wit…
- Edisi
- Vol. 4 No. 4 (2016): August 2016
- ISBN/ISSN
- -
- Deskripsi Fisik
- -
- Judul Seri
- -
- No. Panggil
- 001
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