1 st ICPHS-PoltekkesGorontalo2021

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Aging facial skin can be characterized by the appearance of wrinkles, reduced skin
moisture/dry and rough, and the occurrence of pigmentation such as black spots. Aging is a
natural process associated with degenerative processes, besides external factors such as air
pollution, sunlight, especially ultraviolet (UV) rays can accelerate aging of facial skin. Phenolic
compounds in corn cobs and coffee beans have the potential as a sunscreen that can slow
down the aging process of the skin. This study uses an experimental method. Sunscreen cream
containing corncob extract (10%) and robusta coffee beans (15%) has an IC50 value of 97.34
ppm with a strong antioxidant category and an SPF value of 37 extra protection levels. The
cream was evaluated for physical properties and stability using the cycling test method, then
tested for anti-aging activity with parameters such as wrinkles in vivo using female SpragueDawley rats observed by SEM. The results of the physical evaluation of the cream formula in
the form of organoleptic tests, homogeneity, pH, spreadability, viscosity, and adhesion met the
requirements for the physical evaluation of the cream. The results of the anti-aging activity test
provide a wrinkle score with details of the average wrinkle score on the skin of the animal's paw
with a cream base treatment of 2.5, a test cream of 1.5 and a comparison cream of 1. This
indicates that the combination test cream of cob extract Corn and robusta coffee beans have
the potential to slow down the aging process by protecting the skin from UV exposure.
Keywords: Antiaging, Cob extract, Combination of corn, Robusta coffee bean, Sunscreen

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: .,

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Bahasa

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2021

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D3 Farmasi

Pernyataan Tanggungjawab

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