Skripsi

ANALISIS PENGGUNAAN SEQUENCE 3D SUSCEPTIBILITY WEIGTHED ANGIOGRAPHY PADA PEMERIKSAAN MRI BRAIN DENGAN KLINIS PARKINSON DI INSTALASI RADIOLOGI RS FATMAWATI

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ABSTRACT rnrnBACHELOR OF APPLIED SCIENCE PROGRAM rnIMAGING RADIOLOGY TECHNOLOGY STUDY PROGRAM rnRADIODIAGNOSTICS AND RADIOTHERAPY DEPARTMENT rnHEALTH POLYTECHNIC OF HEALTH MINISTRY rnJAKARTA II rnrnTHESIS, 2025 rnMAHARANI SYAHLA TARUNI rnrnANALYSIS OF 3D SUSCEPTIBILITY-WEIGHTED ANGIOGRAPHY (SWAN) rnSEQUENCE UTILIZATION IN MRI BRAIN EXAMINATIONS WITH CLINICAL rnPARKINSON’S DISEASE AT RADIOLOGY DEPARTMENT OF FATMAWATI rnHOSPITAL rnrn5 Chapters + 41 Pages + 10 Images + 2 Tables + 16 Appendices rnrnParkinson’s disease is a progressive neurodegenerative disorder characterized by both motor and rnnon-motor dysfunction, with increasing prevalence in the elderly population. This condition requires rnadvanced diagnostic modalities, such as Magnetic Resonance Imaging (MRI), which provides rndetailed visualization of brain anatomy and the ability to detect characteristic signs. One of these rnsigns is iron accumulation and the loss of the “swallow tail” sign in the substantia nigra, which can rnbe observed using the 3D Susceptibility-Weighted Angiography (3D SWAN) sequence. This rnresearch aims to analyse the use of the 3D Susceptibility-Weighted Angiography (3D SWAN) rnsequence in MRI brain examinations with clinical Parkinson’s disease undertaken at Radiology rnDepartment of Fatmawati Hospital. The 3D SWAN sequence is applied as a routine protocol due to rnits ability to visualize microvascular brain structures in detail, detect iron deposition, and identify rnthe absence of the “swallow tail” sign in the substantia nigra, a key imaging marker in the patients rnwith Parkinson’s disease. rnThis research applies descriptive qualitative research using a case study approach, conducted at rnthe Radiology Department of Fatmawati Hospital in June 2025 after obtaining Ethical Clearance rn(EC). The population consisted of patients undergoing brain MRI, with a sample of five elderly rnpatients who underwent examinations using the 3D Susceptibility-Weighted Angiography (3D rnSWAN) sequence. Data were collected through among the other things direct observation, in-depth rninterviews with one radiologist and two radiographers each with a minimum of five years of clinical rnexperience and documentation of MRI images and medical records. Research instruments included rnobservation sheets, interview guides, and photographic or MRI image documentation. The collected rndata were processed through data reduction, data display, and triangulation to ensure the validity of rninformation before final interpretation was carried out. rnThe results of this research indicate that the 3D SWAN sequence provides more detailed rnanatomical visualization of the brain, facilitates the detection of the loss of the “swallow tail” sign rnin the substantia nigra, supports early diagnosis, monitors disease progression, and helps distinguish rnParkinson’s disease from other forms of parkinsonism. However, it also has limitations, including rnlonger scanning time and sensitivity to patient movement. rnKeywords : MRI Brain, Parkinson’s Disease, 3D SWAN Sequence, Substantia Nigra, rnSwallow Tail Sign rnReferences : 39 Sources (2015–2024)

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

001.43 MAH a

Penerbit

Jakarta : Jurusan Teknik Radiodiagnostik dan Radioterapi., 2025

Deskripsi Fisik

15 + 41pages: illustration; 21 x 29cm.

Bahasa

Indonesia

ISBN/ISSN

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Klasifikasi

001.43

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

MRI Brain
Parkinson
sequence 3D SWAN
substantia nigra
swallow tail

Info Detail Spesifik

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Pernyataan Tanggungjawab

MAHARANI SYAHLA TARUNI

Versi lain/terkait

Lampiran Berkas

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